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The alpha-1A adrenergic receptor agonist A61603 reduces cardiac polyunsaturated fatty acid and endocannabinoid metabolites associated with inflammation in vivo

INTRODUCTION: Alpha-1-adrenergic receptors (α1-ARs) are G-protein coupled receptors (GPCRs) with three highly homologous subtypes (α1A, α1B, and α1D). Of these three subtypes, only the α1A and α1B are expressed in the heart. Multiple pre-clinical models of heart injury demonstrate cardioprotective r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Metabolomics
Prif Awduron: Willis, Monte S., Ilaiwy, Amro, Montgomery, Megan D., Simpson, Paul C., Jensen, Brian C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437747/
https://ncbi.nlm.nih.gov/pubmed/28533737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-016-1097-3
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