The chromatin remodeler Chd4 maintains embryonic stem cell identity by controlling pluripotency- and differentiation-associated genes

The unique properties of embryonic stem cells (ESCs), including unlimited self-renewal and pluripotent differentiation potential, are sustained by integrated genetic and epigenetic networks composed of transcriptional factors and epigenetic modulators. However, the molecular mechanisms underlying th...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Zhao, Haixin, Han, Zhijun, Liu, Xinyuan, Gu, Junjie, Tang, Fan, Wei, Gang, Jin, Ying
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437254/
https://ncbi.nlm.nih.gov/pubmed/28298436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770248
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