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The herpes simplex virus 1 UL36USP deubiquitinase suppresses DNA repair in host cells via deubiquitination of proliferating cell nuclear antigen

Herpes simplex virus 1 (HSV-1) infection manipulates distinct host DNA-damage responses to facilitate virus proliferation, but the molecular mechanisms remain to be elucidated. One possible HSV-1 target might be DNA damage-tolerance mechanisms, such as the translesion synthesis (TLS) pathway. In TLS...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dong, Xiaodong, Guan, Junhong, Zheng, Chunfu, Zheng, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437251/
https://ncbi.nlm.nih.gov/pubmed/28348081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.778076
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