Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice

Age is characterized by chronic inflammation, leading to synaptic dysfunction and dementia because the clearance of protein waste is reduced. The clearance of proteins depends partly on the permeation of the blood–brain barrier (BBB) or on the exchange of water and soluble contents between the cereb...

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Bibliographische Detailangaben
Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: He, Xiao-fei, Liu, Dong-xu, Zhang, Qun, Liang, Feng-ying, Dai, Guang-yan, Zeng, Jin-sheng, Pei, Zhong, Xu, Guang-qing, Lan, Yue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437122/
https://ncbi.nlm.nih.gov/pubmed/28579942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00144
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