Increased tauopathy drives microglia-mediated clearance of beta-amyloid

Alzheimer disease is characterized by the accumulation of β-amyloid (Aβ) plaques and tau-laden neurofibrillary tangles. Emerging studies suggest that in neurodegenerative diseases, aggregation of one protein species can promote other proteinopathies and that inflammation plays an important role in t...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Chen, Wesley, Abud, Edsel A., Yeung, Stephen T., Lakatos, Anita, Nassi, Trevor, Wang, Jane, Blum, David, Buée, Luc, Poon, Wayne W., Blurton-Jones, Mathew
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918195/
https://ncbi.nlm.nih.gov/pubmed/27339073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0336-1
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