Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice

Age is characterized by chronic inflammation, leading to synaptic dysfunction and dementia because the clearance of protein waste is reduced. The clearance of proteins depends partly on the permeation of the blood–brain barrier (BBB) or on the exchange of water and soluble contents between the cereb...

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Publicado en:Front Mol Neurosci
Autores principales: He, Xiao-fei, Liu, Dong-xu, Zhang, Qun, Liang, Feng-ying, Dai, Guang-yan, Zeng, Jin-sheng, Pei, Zhong, Xu, Guang-qing, Lan, Yue
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437122/
https://ncbi.nlm.nih.gov/pubmed/28579942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00144
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