Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump

Mutations in the neuron-specific α(3) isoform of the Na(+)/K(+)-ATPase are found in patients suffering from Rapid onset Dystonia Parkinsonism and Alternating Hemiplegia of Childhood, two closely related movement disorders. We show that mice harboring a heterozygous hot spot disease mutation, D801Y (...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Isaksen, Toke Jost, Kros, Lieke, Vedovato, Natascia, Holm, Thomas Hellesøe, Vitenzon, Ariel, Gadsby, David C., Khodakhah, Kamran, Lykke-Hartmann, Karin
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436892/
https://ncbi.nlm.nih.gov/pubmed/28472154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006763
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы