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Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2

Migraine is a highly prevalent, debilitating, episodic headache disorder affecting roughly 15% of the population. Familial hemiplegic migraine type 2 (FHM2) is a rare subtype of migraine caused by mutations in the ATP1A2 gene, encoding the α(2) isoform of the Na(+)/K(+)-ATPase, predominantly express...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kros, Lieke, Lykke-Hartmann, Karin, Khodakhah, Kamran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240030/
https://ncbi.nlm.nih.gov/pubmed/30446731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35285-8
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