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Route, mechanism, and implications of proton import during Na(+)/K(+) exchange by native Na(+)/K(+)-ATPase pumps

A single Na(+)/K(+)-ATPase pumps three Na(+) outwards and two K(+) inwards by alternately exposing ion-binding sites to opposite sides of the membrane in a conformational sequence coupled to pump autophosphorylation from ATP and auto-dephosphorylation. The larger flow of Na(+) than K(+) generates ou...

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Bibliografski detalji
Glavni autori: Vedovato, Natascia, Gadsby, David C.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971657/
https://ncbi.nlm.nih.gov/pubmed/24688018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311148
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