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Route, mechanism, and implications of proton import during Na(+)/K(+) exchange by native Na(+)/K(+)-ATPase pumps
A single Na(+)/K(+)-ATPase pumps three Na(+) outwards and two K(+) inwards by alternately exposing ion-binding sites to opposite sides of the membrane in a conformational sequence coupled to pump autophosphorylation from ATP and auto-dephosphorylation. The larger flow of Na(+) than K(+) generates ou...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971657/ https://ncbi.nlm.nih.gov/pubmed/24688018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311148 |
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