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A mathematical model coupling polarity signaling to cell adhesion explains diverse cell migration patterns
Protrusion and retraction of lamellipodia are common features of eukaryotic cell motility. As a cell migrates through its extracellular matrix (ECM), lamellipod growth increases cell-ECM contact area and enhances engagement of integrin receptors, locally amplifying ECM input to internal signaling ca...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436877/ https://ncbi.nlm.nih.gov/pubmed/28472054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005524 |
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