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Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure

AIMS: Combined left ventricular assist device (LVAD) and pharmacological therapy has been proposed to favour myocardial recovery in patients with end-stage heart failure (HF). Clenbuterol (Clen), a β(2)-adrenoceptor (β(2)-AR) agonist, has been used as a part of this strategy. In this study, we inves...

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Detalles Bibliográficos
Publicado en:Cardiovasc Res
Main Authors: Soppa, Gopal K.R., Lee, Joon, Stagg, Mark A., Felkin, Leanne E., Barton, Paul J.R., Siedlecka, Urszula, Youssef, Samuel, Yacoub, Magdi H., Terracciano, Cesare M.N.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436743/
https://ncbi.nlm.nih.gov/pubmed/18178572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvm106
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