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Prolonged mechanical unloading affects cardiomyocyte excitation-contraction coupling, transverse-tubule structure, and the cell surface

Prolonged mechanical unloading (UN) of the heart is associated with detrimental changes to the structure and function of cardiomyocytes. The mechanisms underlying these changes are unknown. In this study, we report the influence of UN on excitation-contraction coupling, Ca(2+)-induced Ca(2+) release...

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Detalhes bibliográficos
Main Authors: Ibrahim, Michael, Al Masri, Abeer, Navaratnarajah, Manoraj, Siedlecka, Urszula, Soppa, Gopal K., Moshkov, Alexey, Al-Saud, Sara Abou, Gorelik, Julia, Yacoub, Magdi H., Terracciano, Cesare M. N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923356/
https://ncbi.nlm.nih.gov/pubmed/20430793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-156638
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