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Impact of Combined Clenbuterol and Metoprolol Therapy on Reverse Remodelling during Mechanical Unloading

BACKGROUND: Clenbuterol (Cl), a β(2) agonist, is associated with enhanced myocardial recovery during left ventricular assist device (LVAD) support, and exerts beneficial remodelling effects during mechanical unloading (MU) in rodent heart failure (HF). However, the specific effects of combined Cl+β(...

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Bibliographische Detailangaben
Hauptverfasser: Navaratnarajah, Manoraj, Siedlecka, Urszula, Ibrahim, Michael, van Doorn, Carin, Soppa, Gopal, Gandhi, Ajay, Shah, Adarsh, Kukadia, Punam, Yacoub, Magdi H., Terracciano, Cesare M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181979/
https://ncbi.nlm.nih.gov/pubmed/25268495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092909
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