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Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase
To study the impact of epigenetic changes on biological functions, the ability to manipulate the epigenetic status of certain genomic regions artificially could be an indispensable technology. “Epigenome editing” techniques have gradually emerged that apply TALE or CRISPR/Cas9 technologies with vari...
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發表在: | PLoS One |
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Main Authors: | , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Public Library of Science
2017
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436701/ https://ncbi.nlm.nih.gov/pubmed/28542388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177764 |
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