Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase

To study the impact of epigenetic changes on biological functions, the ability to manipulate the epigenetic status of certain genomic regions artificially could be an indispensable technology. “Epigenome editing” techniques have gradually emerged that apply TALE or CRISPR/Cas9 technologies with vari...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Yamazaki, Taiga, Hatano, Yu, Handa, Tetsuya, Kato, Sakiko, Hoida, Kensuke, Yamamura, Rui, Fukuyama, Takashi, Uematsu, Takayuki, Kobayashi, Noritada, Kimura, Hiroshi, Yamagata, Kazuo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436701/
https://ncbi.nlm.nih.gov/pubmed/28542388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177764
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