Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase

To study the impact of epigenetic changes on biological functions, the ability to manipulate the epigenetic status of certain genomic regions artificially could be an indispensable technology. “Epigenome editing” techniques have gradually emerged that apply TALE or CRISPR/Cas9 technologies with vari...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Yamazaki, Taiga, Hatano, Yu, Handa, Tetsuya, Kato, Sakiko, Hoida, Kensuke, Yamamura, Rui, Fukuyama, Takashi, Uematsu, Takayuki, Kobayashi, Noritada, Kimura, Hiroshi, Yamagata, Kazuo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436701/
https://ncbi.nlm.nih.gov/pubmed/28542388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177764
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