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Drugging the Cancers Addicted to DNA Repair
Defects in DNA repair can result in oncogenic genomic instability. Cancers occurring from DNA repair defects were once thought to be limited to rare inherited mutations (such as BRCA1 or 2). It now appears that a clinically significant fraction of cancers have acquired DNA repair defects. DNA repair...
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| Publicat a: | J Natl Cancer Inst |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436301/ https://ncbi.nlm.nih.gov/pubmed/28521333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djx059 |
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