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Drugging the Cancers Addicted to DNA Repair
Defects in DNA repair can result in oncogenic genomic instability. Cancers occurring from DNA repair defects were once thought to be limited to rare inherited mutations (such as BRCA1 or 2). It now appears that a clinically significant fraction of cancers have acquired DNA repair defects. DNA repair...
Uloženo v:
| Vydáno v: | J Natl Cancer Inst |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436301/ https://ncbi.nlm.nih.gov/pubmed/28521333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djx059 |
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