TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice

The capsaicin receptor TRPV1 has been widely characterized in the sensory system as a key component of pain and inflammation. A large amount of evidence shows that TRPV1 is also functional in the brain although its role is still debated. Here we report that TRPV1 is highly expressed in microglial ce...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Marrone, Maria Cristina, Morabito, Annunziato, Giustizieri, Michela, Chiurchiù, Valerio, Leuti, Alessandro, Mattioli, Marzia, Marinelli, Sara, Riganti, Loredana, Lombardi, Marta, Murana, Emanuele, Totaro, Antonio, Piomelli, Daniele, Ragozzino, Davide, Oddi, Sergio, Maccarrone, Mauro, Verderio, Claudia, Marinelli, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436240/
https://ncbi.nlm.nih.gov/pubmed/28489079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15292
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