TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice

The capsaicin receptor TRPV1 has been widely characterized in the sensory system as a key component of pain and inflammation. A large amount of evidence shows that TRPV1 is also functional in the brain although its role is still debated. Here we report that TRPV1 is highly expressed in microglial ce...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Marrone, Maria Cristina, Morabito, Annunziato, Giustizieri, Michela, Chiurchiù, Valerio, Leuti, Alessandro, Mattioli, Marzia, Marinelli, Sara, Riganti, Loredana, Lombardi, Marta, Murana, Emanuele, Totaro, Antonio, Piomelli, Daniele, Ragozzino, Davide, Oddi, Sergio, Maccarrone, Mauro, Verderio, Claudia, Marinelli, Silvia
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436240/
https://ncbi.nlm.nih.gov/pubmed/28489079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15292
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