TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice

The capsaicin receptor TRPV1 has been widely characterized in the sensory system as a key component of pain and inflammation. A large amount of evidence shows that TRPV1 is also functional in the brain although its role is still debated. Here we report that TRPV1 is highly expressed in microglial ce...

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發表在:Nat Commun
Main Authors: Marrone, Maria Cristina, Morabito, Annunziato, Giustizieri, Michela, Chiurchiù, Valerio, Leuti, Alessandro, Mattioli, Marzia, Marinelli, Sara, Riganti, Loredana, Lombardi, Marta, Murana, Emanuele, Totaro, Antonio, Piomelli, Daniele, Ragozzino, Davide, Oddi, Sergio, Maccarrone, Mauro, Verderio, Claudia, Marinelli, Silvia
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436240/
https://ncbi.nlm.nih.gov/pubmed/28489079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15292
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