HLA-DP(84Gly) constitutively presents endogenous peptides generated by the class I antigen processing pathway

Classical antigen processing leads to the presentation of antigenic peptides derived from endogenous and exogenous sources for MHC class I and class II molecules, respectively. Here we show that, unlike other class II molecules, prevalent HLA-DP molecules with β-chains encoding Gly84 (DP(84Gly)) con...

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Publicat a:Nat Commun
Autors principals: Yamashita, Yuki, Anczurowski, Mark, Nakatsugawa, Munehide, Tanaka, Makito, Kagoya, Yuki, Sinha, Ankit, Chamoto, Kenji, Ochi, Toshiki, Guo, Tingxi, Saso, Kayoko, Butler, Marcus O., Minden, Mark D., Kislinger, Thomas, Hirano, Naoto
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436232/
https://ncbi.nlm.nih.gov/pubmed/28489076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15244
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