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Mutant IDH1 regulates the tumor-associated immune system in gliomas
Gliomas harboring mutations in isocitrate dehydrogenase 1/2 (IDH1/2) have the CpG island methylator phenotype (CIMP) and significantly longer patient survival time than wild-type IDH1/2 (wtIDH1/2) tumors. Although there are many factors underlying the differences in survival between these two tumor...
Gespeichert in:
Veröffentlicht in: | Genes Dev |
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Hauptverfasser: | , , , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2017
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435890/ https://ncbi.nlm.nih.gov/pubmed/28465358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.294991.116 |
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