Mutant IDH1 regulates the tumor-associated immune system in gliomas

Gliomas harboring mutations in isocitrate dehydrogenase 1/2 (IDH1/2) have the CpG island methylator phenotype (CIMP) and significantly longer patient survival time than wild-type IDH1/2 (wtIDH1/2) tumors. Although there are many factors underlying the differences in survival between these two tumor...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Amankulor, Nduka M., Kim, Youngmi, Arora, Sonali, Kargl, Julia, Szulzewsky, Frank, Hanke, Mark, Margineantu, Daciana H., Rao, Aparna, Bolouri, Hamid, Delrow, Jeff, Hockenbery, David, Houghton, A. McGarry, Holland, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435890/
https://ncbi.nlm.nih.gov/pubmed/28465358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.294991.116
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