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Functional dissection of NEAT1 using genome editing reveals substantial localization of the NEAT1_1 isoform outside paraspeckles

Large numbers of long noncoding RNAs have been discovered in recent years, but only a few have been characterized. NEAT1 (nuclear paraspeckle assembly transcript 1) is a mammalian long noncoding RNA that is important for the reproductive physiology of mice, cancer development, and the formation of s...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Li, Ruohan, Harvey, Alan R., Hodgetts, Stuart I., Fox, Archa H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435860/
https://ncbi.nlm.nih.gov/pubmed/28325845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.059477.116
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