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Highly Ordered Spatial Organization of the Structural Long Noncoding NEAT1 RNAs within Paraspeckle Nuclear Bodies

Paraspeckles (PSPs) are nuclear bodies associated with the retention in the nucleus of specific mRNAs. Two isoforms of a long noncoding RNA (NEAT1_v1/Menε and NEAT1_v2/Menβ) are required for the integrity of PSPs. Here, we analyzed the molecular organization of PSPs by immuno- and in situ hybridizat...

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Detalhes bibliográficos
Main Authors: Souquere, Sylvie, Beauclair, Guillaume, Harper, Francis, Fox, Archa, Pierron, Gérard
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982136/
https://ncbi.nlm.nih.gov/pubmed/20881053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-08-0690
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