NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

Paraspeckles are subnuclear structures formed around nuclear paraspeckle assembly transcript 1 (NEAT1)/MENε/β long noncoding RNA (lncRNA). Here we show that paraspeckles become dramatically enlarged after proteasome inhibition. This enlargement is mainly caused by NEAT1 transcriptional up-regulation...

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Detalhes bibliográficos
Main Authors: Hirose, Tetsuro, Virnicchi, Giorgio, Tanigawa, Akie, Naganuma, Takao, Li, Ruohan, Kimura, Hiroshi, Yokoi, Takahide, Nakagawa, Shinichi, Bénard, Marianne, Fox, Archa H., Pierron, Gérard
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873887/
https://ncbi.nlm.nih.gov/pubmed/24173718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-09-0558
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