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Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling
Prion diseases are neurodegenerative conditions caused by misfolding of the prion protein, leading to conspicuous neuronal loss and intense microgliosis. Recent experimental evidence point towards a protective role of microglia against prion-induced neurodegeneration, possibly through elimination of...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435345/ https://ncbi.nlm.nih.gov/pubmed/28545141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177876 |
| Oznake: |
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