PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarization in cortical spreading depression

Cortical spreading depression is associated with activation of NMDA receptors, which interact with the postsynaptic density protein 95 (PSD-95) that binds to nitric oxide synthase (nNOS). Here, we tested whether inhibition of the nNOS/PSD-95/NMDA receptor complex formation by anti-ischemic compound,...

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Detaylı Bibliyografya
Yayımlandı:J Cereb Blood Flow Metab
Asıl Yazarlar: Kucharz, Krzysztof, Søndergaard Rasmussen, Ida, Bach, Anders, Strømgaard, Kristian, Lauritzen, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2016
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435282/
https://ncbi.nlm.nih.gov/pubmed/27107027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16645595
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