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Inference of Epistatic Effects Leading to Entrenchment and Drug Resistance in HIV-1 Protease
Understanding the complex mutation patterns that give rise to drug resistant viral strains provides a foundation for developing more effective treatment strategies for HIV/AIDS. Multiple sequence alignments of drug-experienced HIV-1 protease sequences contain networks of many pair correlations which...
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| Publicado no: | Mol Biol Evol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435099/ https://ncbi.nlm.nih.gov/pubmed/28369521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx095 |
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