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Pharmacokinetics and Acid Suppressant Efficacy of Esomeprazole after Intravenous, Oral, and Subcutaneous Administration to Healthy Beagle Dogs

BACKGROUND: Esomeprazole is an S‐enantiomer of omeprazole that has favorable pharmacokinetics and efficacious acid suppressant properties in humans. However, the pharmacokinetics and effects on intragastric pH of esomeprazole in dogs have not been reported. OBJECTIVE: To determine the pharmacokineti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Vet Intern Med
Prif Awduron: Hwang, J.‐H., Jeong, J.‐W., Song, G.‐H., Koo, T.‐S., Seo, K.‐W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435062/
https://ncbi.nlm.nih.gov/pubmed/28407418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.14713
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