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Association of Two Polymorphic Codons in P53 and ABCC1 Promoter with Prostate Cancer

BACKGROUND: In prostate cancer, mutated p53 alleles typically contain missense single-base substitution in codon 72 that resides within exons 5-8. Stable p53 proteins in tumor cell nuclei have been associated with malignancy. A role of p53 is the regulation of drug transporters like ABCC1 (MRP1) by...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Iran J Biotechnol
Egile Nagusiak: Behfarjam, Farinaz, Rostamzadeh, Jalal, Zarei, Mohammad Ali, Nikkhoo, Bahram
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Institute of Genetic Engineering and Biotechnology 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434987/
https://ncbi.nlm.nih.gov/pubmed/28959281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/ijb.1096
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