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Association of Two Polymorphic Codons in P53 and ABCC1 Promoter with Prostate Cancer
BACKGROUND: In prostate cancer, mutated p53 alleles typically contain missense single-base substitution in codon 72 that resides within exons 5-8. Stable p53 proteins in tumor cell nuclei have been associated with malignancy. A role of p53 is the regulation of drug transporters like ABCC1 (MRP1) by...
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| Publicado no: | Iran J Biotechnol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Institute of Genetic Engineering and Biotechnology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5434987/ https://ncbi.nlm.nih.gov/pubmed/28959281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/ijb.1096 |
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