Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody–Associated Vasculitis

OBJECTIVE: To identify risk alleles relevant to the causal and biologic mechanisms of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). METHODS: A genome‐wide association study and subsequent replication study were conducted in a total cohort of 1,986 cases of AAV (patients wit...

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Опубликовано в: :Arthritis Rheumatol
Главные авторы: Merkel, Peter A., Xie, Gang, Monach, Paul A., Ji, Xuemei, Ciavatta, Dominic J., Byun, Jinyoung, Pinder, Benjamin D., Zhao, Ai, Zhang, Jinyi, Tadesse, Yohannes, Qian, David, Weirauch, Matthew, Nair, Rajan, Tsoi, Alex, Pagnoux, Christian, Carette, Simon, Chung, Sharon, Cuthbertson, David, Davis, John C., Dellaripa, Paul F., Forbess, Lindsy, Gewurz‐Singer, Ora, Hoffman, Gary S., Khalidi, Nader, Koening, Curry, Langford, Carol A., Mahr, Alfred D., McAlear, Carol, Moreland, Larry, Seo, E. Philip, Specks, Ulrich, Spiera, Robert F., Sreih, Antoine, St.Clair, E. William, Stone, John H., Ytterberg, Steven R., Elder, James T., Qu, Jia, Ochi, Toshiki, Hirano, Naoto, Edberg, Jeffrey C., Falk, Ronald J., Amos, Christopher I., Siminovitch, Katherine A.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Vasculitis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434905/
https://ncbi.nlm.nih.gov/pubmed/28029757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40034
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