IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis

Granulomatosis with polyangiitis (Wegener's) is a rare autoimmune neutrophil-mediated vasculitis that can cause renal disease and mucosal manifestations. Antineutrophil cytoplasmic antibodies (ANCA) are present in many patients, vary in level over time, and induce neutrophil activation through...

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Главные авторы: Kelley, James M., Monach, Paul A., Ji, Chuanyi, Zhou, Yebin, Wu, Jianming, Tanaka, Sumiaki, Mahr, Alfred D., Johnson, Sharleen, McAlear, Carol, Cuthbertson, David, Carette, Simon, Davis, John C., Dellaripa, Paul F., Hoffman, Gary S., Khalidi, Nader, Langford, Carol A., Seo, Phillip, St. Clair, E. William, Specks, Ulrich, Stone, John H., Spiera, Robert F., Ytterberg, Steven R., Merkel, Peter A., Edberg, Jeffrey C., Kimberly, Robert P.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251158/
https://ncbi.nlm.nih.gov/pubmed/22147912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109227109
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