Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody–Associated Vasculitis

OBJECTIVE: To identify risk alleles relevant to the causal and biologic mechanisms of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). METHODS: A genome‐wide association study and subsequent replication study were conducted in a total cohort of 1,986 cases of AAV (patients wit...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Merkel, Peter A., Xie, Gang, Monach, Paul A., Ji, Xuemei, Ciavatta, Dominic J., Byun, Jinyoung, Pinder, Benjamin D., Zhao, Ai, Zhang, Jinyi, Tadesse, Yohannes, Qian, David, Weirauch, Matthew, Nair, Rajan, Tsoi, Alex, Pagnoux, Christian, Carette, Simon, Chung, Sharon, Cuthbertson, David, Davis, John C., Dellaripa, Paul F., Forbess, Lindsy, Gewurz‐Singer, Ora, Hoffman, Gary S., Khalidi, Nader, Koening, Curry, Langford, Carol A., Mahr, Alfred D., McAlear, Carol, Moreland, Larry, Seo, E. Philip, Specks, Ulrich, Spiera, Robert F., Sreih, Antoine, St.Clair, E. William, Stone, John H., Ytterberg, Steven R., Elder, James T., Qu, Jia, Ochi, Toshiki, Hirano, Naoto, Edberg, Jeffrey C., Falk, Ronald J., Amos, Christopher I., Siminovitch, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Vasculitis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434905/
https://ncbi.nlm.nih.gov/pubmed/28029757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40034
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