Targeting resolution of neuroinflammation after ischemic stroke with a lipoxin A(4) analog: Protective mechanisms and long‐term effects on neurological recovery

BACKGROUND: Resolution of inflammation is an emerging new strategy to reduce damage following ischemic stroke. Lipoxin A(4) (LXA (4)) is an anti‐inflammatory, pro‐resolution lipid mediator that reduces neuroinflammation in stroke. Since LXA (4) is rapidly inactivated, potent analogs have been synthe...

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Dades bibliogràfiques
Publicat a:Brain Behav
Autors principals: Hawkins, Kimberly E., DeMars, Kelly M., Alexander, Jon C., de Leon, Lauren G., Pacheco, Sean C., Graves, Christina, Yang, Changjun, McCrea, Austin O., Frankowski, Jan C., Garrett, Timothy J., Febo, Marcelo, Candelario‐Jalil, Eduardo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434193/
https://ncbi.nlm.nih.gov/pubmed/28523230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.688
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