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Sustained Neurological Recovery after Stroke in Aged Rats Treated with a Novel Prostacyclin Analog

BACKGROUND AND PURPOSE: Targeting the prostacyclin/IP receptor to reduce stroke injury has been hindered by the lack of selective drugs. MRE-269 is the active metabolite of selexipag showing a very high selectivity toward the IP receptor. Selexipag has been recently approved for clinical use in pulm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Stroke
Hauptverfasser: Yang, Changjun, DeMars, Kelly M., Alexander, Jon C., Febo, Marcelo, Candelario-Jalil, Eduardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508605/
https://ncbi.nlm.nih.gov/pubmed/28588054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.016474
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