Targeting resolution of neuroinflammation after ischemic stroke with a lipoxin A(4) analog: Protective mechanisms and long‐term effects on neurological recovery

BACKGROUND: Resolution of inflammation is an emerging new strategy to reduce damage following ischemic stroke. Lipoxin A(4) (LXA (4)) is an anti‐inflammatory, pro‐resolution lipid mediator that reduces neuroinflammation in stroke. Since LXA (4) is rapidly inactivated, potent analogs have been synthe...

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Bibliographische Detailangaben
Veröffentlicht in:Brain Behav
Hauptverfasser: Hawkins, Kimberly E., DeMars, Kelly M., Alexander, Jon C., de Leon, Lauren G., Pacheco, Sean C., Graves, Christina, Yang, Changjun, McCrea, Austin O., Frankowski, Jan C., Garrett, Timothy J., Febo, Marcelo, Candelario‐Jalil, Eduardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434193/
https://ncbi.nlm.nih.gov/pubmed/28523230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.688
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