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Kinetic and Molecular Analysis of Nuclear Export Factor CRM1 Association with Its Cargo In Vivo

The nucleocytoplasmic transport receptor CRM1 mediates the export of macromolecules from the nucleus to the cytoplasm by forming a ternary complex with a cargo molecule and RanGTP. The in vivo mechanism of CRM1 export complex formation and its mobility throughout the nucleus have not been fully eluc...

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Detalhes bibliográficos
Main Authors: Daelemans, Dirk, Costes, Sylvain V., Lockett, Stephen, Pavlakis, George N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC543413/
https://ncbi.nlm.nih.gov/pubmed/15632073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.2.728-739.2005
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