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IL-18-dependent NKG2D ligand upregulation on accessory cells is mediated by the PI3K/GSK-3 pathway

NK cells are critical for the control of viral infections. Studies have shown that efficient NK cell activation in response to infection with VV in vivo requires multiple pathways, including the NKG2D pathway. We have recently shown that IL-18 is necessary for the activation of NK cells through upre...

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Detalles Bibliográficos
Publicado en:J Leukoc Biol
Main Authors: Brandstadter, Joshua D., Chen, Huiyao, Jiang, Songfu, Huang, Xiaopei, Yang, Yiping
Formato: Artigo
Idioma:Inglês
Publicado: Society for Leukocyte Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433856/
https://ncbi.nlm.nih.gov/pubmed/28283665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2A0816-342R
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