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Metabolic profiling by gas chromatography-mass spectrometry of energy metabolism in high-fat diet-fed obese mice

A novel, selective and sensitive single-ion monitoring (SIM) gas chromatography-mass spectrometry (GCMS) method was developed and validated for the determination of energy metabolites related to glycolysis, the tricarboxylic acid (TCA) cycle, glutaminolysis, and fatty acid β-oxidation. This assay us...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Patel, Daxesh P., Krausz, Kristopher W., Xie, Cen, Beyoğlu, Diren, Gonzalez, Frank J., Idle, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433781/
https://ncbi.nlm.nih.gov/pubmed/28520815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177953
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