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Metabolic profiling by gas chromatography-mass spectrometry of energy metabolism in high-fat diet-fed obese mice

A novel, selective and sensitive single-ion monitoring (SIM) gas chromatography-mass spectrometry (GCMS) method was developed and validated for the determination of energy metabolites related to glycolysis, the tricarboxylic acid (TCA) cycle, glutaminolysis, and fatty acid β-oxidation. This assay us...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Patel, Daxesh P., Krausz, Kristopher W., Xie, Cen, Beyoğlu, Diren, Gonzalez, Frank J., Idle, Jeffrey R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433781/
https://ncbi.nlm.nih.gov/pubmed/28520815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177953
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