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Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus

A new enzyme homologous to phosphotriesterase was identified from the bacterium Geobacillus stearothermophilus (GsP). This enzyme belongs to the amidohydrolase family and possesses the ability to hydrolyze both lactone and organophosphate (OP) compounds, making it a phosphotriesterase-like lactonase...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Hawwa, Renda, Aikens, John, Turner, Robert J., Santarsiero, Bernard D., Mesecar, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433624/
https://ncbi.nlm.nih.gov/pubmed/19615330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.06.005
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