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A covalent antagonist for the human adenosine A(2A) receptor
The structure of the human A(2A) adenosine receptor has been elucidated by X-ray crystallography with a high affinity non-xanthine antagonist, ZM241385, bound to it. This template molecule served as a starting point for the incorporation of reactive moieties that cause the ligand to covalently bind...
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| 出版年: | Purinergic Signal |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Netherlands
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5432479/ https://ncbi.nlm.nih.gov/pubmed/27915383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9549-9 |
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