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Astrocyte-Specific Insulin-Like Growth Factor-1 Gene Transfer in Aging Female Rats Improves Stroke Outcomes

Middle aged female rats sustain larger stroke infarction and disability than younger female rats. This older group also shows age-related reduction of insulin like growth factor (IGF)-1 in serum and in astrocytes, a cell type necessary for post stroke recovery. To determine the impact of astrocytic...

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Bibliographische Detailangaben
Veröffentlicht in:Glia
Hauptverfasser: Okoreeh, Andre, Bake, Shameena, Sohrabji, Farida
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432389/
https://ncbi.nlm.nih.gov/pubmed/28317235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23142
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