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The Neurotoxic Effects of Estrogen on Ischemic Stroke in Older Female Rats Is Associated with Age-Dependent Loss of Insulin-Like Growth Factor-1

Hormone therapy to postmenopausal females increases the risk and severity of ischemic stroke. Our previous work using an animal model of menopause (reproductive senescence) shows that middle cerebral artery occlusion (MCAo) causes a larger cortical–striatal infarct in this older acyclic group compar...

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Detalhes bibliográficos
Main Authors: Selvamani, Amutha, Sohrabji, Farida
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887690/
https://ncbi.nlm.nih.gov/pubmed/20484627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0761-10.2010
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