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An Antagomir to MicroRNA Let7f Promotes Neuroprotection in an Ischemic Stroke Model

We previously showed that middle-aged female rats sustain a larger infarct following experimental stroke as compared to younger female rats, and paradoxically, estrogen treatment to the older group is neurotoxic. Plasma and brain insulin-like growth factor-1 (IGF-1) levels decrease with age. However...

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Detalhes bibliográficos
Main Authors: Selvamani, Amutha, Sathyan, Pratheesh, Miranda, Rajesh C., Sohrabji, Farida
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290559/
https://ncbi.nlm.nih.gov/pubmed/22393433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032662
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