Microgravity induces inhibition of osteoblastic differentiation and mineralization through abrogating primary cilia

It is well documented that microgravity in space environment leads to bone loss in astronauts. These physiological changes have also been validated by human and animal studies and modeled in cell-based analogs. However, the underlying mechanisms are elusive. In the current study, we identified a nov...

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Pubblicato in:Sci Rep
Autori principali: Shi, Wengui, Xie, Yanfang, He, Jinpeng, Zhou, Jian, Gao, Yuhai, Wei, Wenjun, Ding, Nan, Ma, Huiping, Xian, Cory J., Chen, Keming, Wang, Jufang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431935/
https://ncbi.nlm.nih.gov/pubmed/28500304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02049-9
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